Cardio facial syndrome velo

Craniofacial Anomalies. How Can I Help? Shop Amazon Smile. Box , Chattanooga, TN Download PDF information sheet.

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Velocardiofacial Syndrome (VCFS)

Velo-Cardio-Facial Syndrome

Velocardiofacial syndrome VCFS is a genetic condition that is sometimes hereditary. VCFS is characterized by a combination of medical problems that vary from child to child. These medical problems include: cleft palate, or an opening in the roof of the mouth, and other differences in the palate; heart defects; problems fighting infection; low calcium levels; differences in the way the kidneys are formed or work; a characteristic facial appearance; learning problems; and speech and feeding problems. The name velocardiofacial syndrome comes from the Latin words 'velum' meaning palate, "cardia" meaning heart and "facies" having to do with the face. Not all of these identifying features are found in each child who is born with VCFS.
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Atlas-based white matter analysis in individuals with velo-cardio-facial syndrome (22q11.2 deletion syndrome) and unaffected siblings

Individuals with VCFS present with deficits in cognition and social functioning, high risk of psychiatric disorders, volumetric reductions in gray and white matter WM and some alterations of the WM microstructure. The goal of the current study was to characterize the WM microstructural differences in individuals with VCFS and unaffected siblings, and the correlation of WM microstructure with neuropsychological performance. We hypothesized that individuals with VCFS would have decreased indices of WM microstructure fractional anisotropy FA , axial diffusivity AD and radial diffusivity RD , particularly in WM tracts to the frontal lobe, and that these measures would be correlated with cognitive functioning. Thirty-three individuals with VCFS 21 female and 16 unaffected siblings 8 female participated in DTI scanning and neuropsychological testing.
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Skip to search form Skip to main content. Velo-cardio-facial syndrome: a distinctive behavioral phenotype. Shprintzen Published in Mental retardation and developmental disabilities…. Velo-cardio-facial syndrome VCFS is the most common contiguous gene disorder and one of the most common multiple anomaly syndromes in humans. Over anomalies have been delineated in the syndrome; the most common of which are the behavioral manifestations.
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